The development and testing of a radio labelled anti-transferrin scFv for radiotherapy

The human transferrin receptor (CD71) is a ubiquitously expressed internalising glycoprotein involved in iron homeostasis. Expression of the transferrin receptor is found to be greatly upregulated in tumour cells and, as such, it offers a useful target in the development of immunotherapeutic agents...

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Bibliographic Details
Main Author: Godfrey, Samuel Nathan
Published: University of Kent 2012
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.594200