Synthesis of novel allosteric agonists and allosteric modulators for nicotinic acetylcholine receptors
In healthy individuals, the α7 and α4β2 nAChRs are concentrated in regions of the brain involved with learning, cognition and memory, which are relevant to diseases such as Alzheimer’s disease. Hence, these receptors have become significant from a pharmacological and drug discovery perspective. The...
Main Author: | |
---|---|
Published: |
University College London (University of London)
2013
|
Subjects: | |
Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.594374 |