Synthesis of oxygen containing heterocycles as potential IDO inhibitors

One potentially attractive approach to cancer therapy is to recruit the body’s own immune system to reject solid tumours. The enzyme indoleamine 2,3-dioxygenase (IDO) has been shown to play a major role in supressing immune response, and there is now growing evidence to support the hypothesis that i...

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Bibliographic Details
Main Author: Carvalho, Catarina
Published: University of Nottingham 2013
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.594817