Regulation of expression and cellular release of acetylcholinesterase

Acetylcholinesterase (AChE) is a hydrolytic enzyme which has been linked to the pathological progression of the neurodegenerative disease, Alzheimer’s disease (AD). AD is thought to be driven by the toxic amyloid-β (Aβ) peptide, which derives from proteolytic cleavage of amyloid precursor protein (A...

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Bibliographic Details
Main Author: Hicks, David
Other Authors: Turner, Tony ; Nalivaeva, Natasha
Published: University of Leeds 2013
Subjects:
570
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.595159