The role of eukaryotic initiation factor 4F in translation initiation by linear scanning and internal ribosome binding

The experiments described in this dissertation used the rabbit reticulocyte lysate translation assay system to investigate what parts of the eIF4F complex are needed for (a) initiation by the scanning ribosome mechanism, and (b) IRES-dependent initiation. To this end, an affinity chromatography meth...

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Bibliographic Details
Main Author: Ali, I. K.
Published: University of Cambridge 2002
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.595445