Lipotoxicity and the role of translationally controlled tumour protein (TCTP) in pancreatic β-cell survival

Introduction: Diabetes affects more than 346 million individuals worldwide. Some 90% of diabetics have type 2 diabetes mellitus, which is frequently associated with obesity and hyperlipidemia as well as hyperglycaemia. There is ample evidence that fatty acids become toxic (lipotoxicity) when present...

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Bibliographic Details
Main Author: Hayward, K. L.
Published: University of the West of England, Bristol 2014
Subjects:
572
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.596049