Studies toward the configurational assignment and total synthesis of reidispongiolide A

Reidispongiolide A (10) is a cytotoxic, marine macrolide that exerts inhibition of cell growth through actin-binding. Of particular interest is its efficacy against multi-drug resistant cancer cell lines. At the outset of the project the stereochemical configuration of reidispongiolide A was uncerta...

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Bibliographic Details
Main Author: Ashton, K. S.
Published: University of Cambridge 2005
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.596190