Enzymology of type I modular polyketide synthases

Modular type I polyketide synthase (PKSs), for example the 6-deoxyerythronolide B synthase (DEBS) responsible for formation of the aglycone core of erythromycin A, are giant, multifunctional enzyme complexes that catalyse the orchestrated assembly line biosynthesis of antibiotic polyketide natural p...

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Bibliographic Details
Main Author: Bali, Shilpa
Published: University of Cambridge 2007
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.596310