Endocytosis and recycling of angiotensin II receptors

The main finding of this work is evidence that the AT<sub>1</sub>R is constitutively active and can undergo endocytosis and subsequent recycling in the absence of agonist. The application of a putative inverse agonist was able to increase the relative surface density in the presence of a...

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Bibliographic Details
Main Author: Ball, S. L. R.
Published: University of Cambridge 2003
Subjects:
572
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.596314