Mechanisms of P-Rex1 regulation
First, regulation of its subcellular localisation: the upstream activators of P-Rex1, Gβγs and PI(3,4,5)P<sub>3</sub>, as well as its downstream effector Rac, are all intrinsically associated with the plasma membrane. Yet in resting cells P-Rex1 is mainly cytosolic. Here, it is shown tha...
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University of Cambridge
2010
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.596342 |