Structural analysis of an HIV-neutralizing protein and its complex with native viral gp120 : implications for antiviral drug design
I present a three-dimensional structural analysis of (1) the simian immunodeficiency virus (SIV) gp120-gp41 envelope glycoprotein complex, (2) D1D2-Igαtp, a CD4-antibody construct with extreme HIV-neutralizing capability, and (3) the complex of D1D2-Igαtp with native SIV gp120, using cryo electron t...
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University of Cambridge
2008
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Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.596573 |