Structural analysis of an HIV-neutralizing protein and its complex with native viral gp120 : implications for antiviral drug design
I present a three-dimensional structural analysis of (1) the simian immunodeficiency virus (SIV) gp120-gp41 envelope glycoprotein complex, (2) D1D2-Igαtp, a CD4-antibody construct with extreme HIV-neutralizing capability, and (3) the complex of D1D2-Igαtp with native SIV gp120, using cryo electron t...
Main Author: | Bennett, A. E. |
---|---|
Published: |
University of Cambridge
2008
|
Subjects: | |
Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.596573 |
Similar Items
-
Studies on synthetic peptides from HIV-1 gp120 for the development of an AIDS vaccine
by: Cotton, Graham J.
Published: (1994) -
Characterisation of viral macromolecular complexes and their use in biotechnology
by: Holmes, Kristopher Kurt David
Published: (2012) -
Viral RNA and mammalian protein synthesis
by: Mathews, M. B.
Published: (1970) -
Kinetics and modulation of the viral Ion channel vpu from HIV-1
by: Judge, Peter J.
Published: (2008) -
The interaction of human cytomegalovirus immediate early proteins with viral and cellular factors
by: Fairley, J. A.
Published: (1999)