Synthesis of an advanced macrolide intermediate for the aplyronines
Aplyronine A (5) is a polyketide metabolite isolated in microscopic quantities from the Japanese sea hare <i>Aplysia kurodai</i> by the Yamada group. Aplyronine A displays potent cytotoxic activity both <i>in vitro</i> and <i>in vivo</i>, and has been shown to act...
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University of Cambridge
2001
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.596715 |