The recognition of HLA-B27 by CD4+ T lymphocytes
Studies in B27 transgenic animal models of the spondyloarthropathies (SpA) have demonstrated a requirement for HLA-B27, CD4+ T cells, and bacteria to induce arthritis. This has led to the hypothesis that CD4+ T cells, which usually interact with MHC class II molecules, might recognise HLA-B27. The a...
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University of Cambridge
2002
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Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.596838 |