The molecular pathogenesis of Huntington's disease : the role of molecular chaperones and methods of modulation of polyglutamine-induced aggregate formation and cell death
The aim of my project was to investigate whether overexpression of specific heat shock proteins and treatment with pharmacological agents could modify intracellular aggregate formation and influence cell death. I used a cell culture of Huntington's disease in which the mutant huntingtin protein...
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University of Cambridge
2002
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.597295 |