Long-range functional interactions between genes and regulatory elements

The mouse b-globin locus contains four genes that are expressed throughout development in the same order they are arranged along chromosome 7. Upstream of the genes is a powerful regulatory element called the locus control region (LCR). The LCR is absolutely required for high-level expression of the...

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Bibliographic Details
Main Author: Carter, D. P. F.
Published: University of Cambridge 2004
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.597329