High-throughput screening and biochemical characterization of human chromatin remodelers

This thesis describes the high-throughput screening of chrome/PHD domain constructs from a number of chromatin remodelers and subsequent biochemical and biophysical characterization of several constructs of human CHD3, CHD4 and CHD5. Results from NMR spectroscopy, size exclusion chromatography and s...

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Bibliographic Details
Main Author: Chen, Y.
Published: University of Cambridge 2010
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.597532