Towards a better understanding of non-synonymous single nucleotide polymorphisms : exploring new methods for analysing their pathological implications
One of the two objectives of this thesis is to design a new method that predicts the structural effects of nsSNPs in proteins by considering structural information alone. The other objectives of this thesis are to develop new methods that model protein or domain complex structures at the atomic leve...
Main Author: | |
---|---|
Published: |
University of Cambridge
2008
|
Subjects: | |
Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.597577 |