Dynamics of cell cycle perturbations and cell death by topoisomerase inhibitors in human B-lymphoma cell lines

This study investigates the relationship between cell cycle perturbations and apoptosis, principally in two human B-lymphoma cell lines with different genotypes after exposure to four topoisomerase inhibitors, CPT, DOX, VP-16 and ICRF-193. Both cell lines (DoHH2 and SU-DHL-4) overexpress bcl-2 due t...

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Bibliographic Details
Main Author: Chin, S.-F.
Published: University of Cambridge 1997
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.597606