The function of Smad-interacting factors in neuroectoderm differentiation of human embryonic stem cells

To further understand the molecular mechanisms involving Activin/Nodal signalling in pluripotency, I studied in hESCs the function of two Smad-binding partners, Smad-Interacting Protein 1 (SIP1) and Ectodermin, which are involved in neuroectoderm specification in amphibians and in the mouse. This re...

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Bibliographic Details
Main Author: Chng, Z.
Published: University of Cambridge 2010
Subjects:
611
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.597623