CDC20 function, regulation and proteolysis
The destruction of mitotic cyclins and other key regulators uses ubiquitin mediated proteolysis controlled via the activation of the ubiquitin ligase the Anaphase Promoting Complex/Cyclosome (APC/C), and its adaptor proteins Cdc20 and Cdh1. The spindle assembly checkpoint coordinates the APC/C with...
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University of Cambridge
2007
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Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.597750 |