Splicing regulation by polypyrimidine tract binding protein minimal repressor domain
Polypyrimidine Tract Binding protein (PTB/hnRNPI) is a negative splicing regulator containing four RNA recognition motifs (RRM). The <i>Tpm1</i> exon 3 is repressed in smooth-muscle and PTB is a regulator of this splicing event. Repression of this exon is dependent on flanking PTB bindin...
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University of Cambridge
2010
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Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.597803 |