Investigating reversible drug-DNA interactions in the major groove
In this work a newly developed application of the PCR has been employed in conjunction with footprinting techniques to probe the molecular determinants of the drug-DNA recognition process. Hitherto this methodology has been mainly used to study minor groove association; here it has been adapted to s...
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University of Cambridge
2001
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.598193 |