The crystallographic analysis of the Bacillus thuringiensis delta-endotoxin Cry1Ac, on its own and in a complex with its receptor ligand

Cry toxins are produced as inactive protoxins and require proteolytic processing (activation) within the midguts of susceptible insect larvae. Activated toxins then bind to high affinity receptor molecules on the midgut epithelium, leading to membrane insertion and pore-formation. This study is the...

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Bibliographic Details
Main Author: Derbyshire, D. J.
Published: University of Cambridge 2000
Subjects:
590
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.598510