Modulation of the thermo- and hypotonicity-sensitive ion channel TRPV4
In this thesis, the role of transient receptor potential vanilloid 4 (TRPV4) in mechanical hyperalgesia induced by inflammatory mediators and second-messenger pathways was investigated. The hypotonicity-activated [Ca<sup>2+</sup>]<sub>I</sub> increase in HEK293 cells transien...
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University of Cambridge
2008
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.598933 |