Signalling pathways underlying sensitization of TRPV1 by RET receptors

Here I report that artemin, a member of the glial cell line-derived neurontrophic factor (GDNF) family, can potentiate TRPV1 activity. Analysis of capsaicin-evoked Ca<sup>2+</sup> transients in isolated mouse dorsal root ganglion (DRG) neurons and neuro-2a cells revealed a rapid, potent...

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Bibliographic Details
Main Author: Gu, C.
Published: University of Cambridge 2010
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.599771