Type 1 insulin-like growth factor signalling in malignant melanoma

Novel therapeutic strategies are sorely required for malignant melanoma, which has been shown to overexpress the type 1 insulin-like growth factor receptor (IGFIR) compared benign naevi. The 10Ft R mediates many features of the malignant phenotype and is an attractive anti-cancer therapeutic target....

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Bibliographic Details
Main Author: Goodfellow, Mark
Published: University of Oxford 2013
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.599998