Imprinting at the mouse Gnas cluster
At the imprinted mouse Gnas locus, expression of Nesp in the growing oocyte is required for methylation of the downstream Nespas-Gnasxl DMR and ExonlA DMR; resulting in silencing of Gnasxl and ExonlA, and expression of Gnas on the maternal allele. On the paternal allele, the somatic Nesp promoter is...
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University of Oxford
2012
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.600233 |