Glucocorticoids, 11β-hydroxysteroid dehydrogenase type 1 and the aged phenotype

Cushing’s syndrome is characterised by changes in body composition and cardiovascular disease risk profiles that have similarities to the aged phenotype. 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) converts inactive glucocorticoids(GCs) to their active form (cortisone to cortisol in humans)....

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Bibliographic Details
Main Author: Hassan-Smith, Zaki K.
Published: University of Birmingham 2014
Subjects:
610
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.600361