Investigating the consequences of chromosome abnormalities arising during pre-implantation development of the mouse

The majority of human pre-implantation embryos created through in vitro fertilization (IVF) are mosaic as they are constituted of a mixture of diploid and aneuploid cells. Chromosome abnormalities are widely believed to contribute towards the relatively low success rates of IVF treatment. Consequent...

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Bibliographic Details
Main Author: Bolton, Helen Louise
Published: University of Cambridge 2014
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.600529