Investigating the role of nicotinamide phosphoribosyltransferase (NAMPT) in cartilage catabolism

NAMPT (nicotinamide phosphoribosyltransferase) is a universally expressed protein elevated in the serum and synovial fluid of rheumatoid arthritis (RA) sufferers. NAMPT is a rate-limiting enzyme in the biosynthesis of (nicotinamide adenine dinucleotide) NAD+, an essential cellular coenzyme, and has...

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Bibliographic Details
Main Author: Evans, Laura
Published: Cardiff University 2013
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.600553