Investigating the role of nicotinamide phosphoribosyltransferase (NAMPT) in cartilage catabolism

Investigating the role of nicotinamide phosphoribosyltransferase (NAMPT) in cartilage catabolism

NAMPT (nicotinamide phosphoribosyltransferase) is a universally expressed protein elevated in the serum and synovial fluid of rheumatoid arthritis (RA) sufferers. NAMPT is a rate-limiting enzyme in the biosynthesis of (nicotinamide adenine dinucleotide) NAD+, an essential cellular coenzyme, and has...

Full description

Bibliographic Details
Main Author:	Evans, Laura
Published:	Cardiff University 2013
Subjects:	616.7 R Medicine (General)
Online Access:	http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.600553

Similar Items

Nicotinamide adenine dinucleotide biosynthesis enzymes in rheumatoid arthritis
by: Moideen, Abdul Nazeer
Published: (2016)

Investigating the chondrogenic phenotype in clinically relevant cells : the effect of hTERT expression
by: Dale, Tina Patricia
Published: (2016)

Studies of cartilage degradation in vivo
by: Al-Duaij, Ahmed Yousuf Mohamed
Published: (1985)

Death receptor 3 : a regulator of bone turnover and new target for therapy for osteoporosis?
by: Collins, Fraser
Published: (2013)

An examination of blood oxygen level dependent functional magnetic resonance imaging methods in analysing chronic non-malignant pain patients' responses to non -painful pain stimuli
by: Taylor, Ann
Published: (2012)

Three-dimensional structured hybrid scaffolds for enhanced bone formation
by: Baba Ismail, Yanny Marliana
Published: (2016)

Self-reported physical activity levels : measurement and assessment in community dwelling adults with, or at risk of, osteoarthritis
by: Smith, Robert
Published: (2017)

An in vitro study of the chondrogenic and immunomodulatory properties of mesenchymal stem cells from the osteoarthritic joint
by: Garcia, John K.
Published: (2017)

Assessing pain and inflammation in arthritis using novel imaging methods
by: Jordan, Lauren
Published: (2016)

Characterisation of vascular dysfunction in a murine model of rheumatoid arthritis
by: Williams, Jessica
Published: (2016)

Musculoskeletal ultrasound imaging : an exploration of physiotherapists' interests and use in practice
by: Innes, Sue
Published: (2017)

Lateral versus posterior approach to shoulder injection in patients with subacromial impingement syndrome : a mixed methods study
by: Ogbeivor, Collins A. O.
Published: (2017)

Methodological challenges in treatment mediation analysis : examples from studies targeting psychological factors in patients with musculoskeletal pain
by: Mansell, Gemma
Published: (2016)

Media constructions of 'arthritis' : a mixed methods qualitative study
by: Rowley, Rebecca
Published: (2016)

General practitioners' attitudes, beliefs and behaviours regarding exercise for chronic knee pain
by: Cottrell, Elizabeth
Published: (2016)

Attitudes, beliefs and physical activity in older adults with knee pain
by: Quicke, Jonathan
Published: (2016)

Differentiation of osteoblasts to osteocytes in 3D type I collagen gels : a novel tool to study osteocyte responses to mechanical loading
by: Scully, Nicole
Published: (2015)

Clinical and epigenetic factors underlying treatment refractory Rheumatoid Arthritis
by: Baxter, Derek
Published: (2014)

The interaction of transforming growth factor beta and pro-inflammatory signalling in peritoneal fibrosis
by: Bodenham, Tanya Jayne
Published: (2015)

Hyaluronan and CD44 control of cell fate
by: Woods, Emma
Published: (2016)

Altered leukocyte signalling thresholds in rheumatoid arthritis through changes in the function of the protein tyrosine phosphatase PTPN22/LYP
by: Bayley, Rachel
Published: (2014)

ELR+ CXC chemokine signalling in cartilage homeostasis
by: Sherwood, Joanna
Published: (2011)

Cellular and molecular response to mechanical articular cartilage injury
by: Eltawil, Noha
Published: (2010)

An investigation into the roles of lysosomal proteinases, particularly cathepsin B, in cartilage proteoglycan degradation
by: Adcocks, Clair
Published: (1999)

Development of a novel 3D human cartilage model system to investigate changes in cartilage associated with osteoarthritis
by: Heil, Andreas
Published: (2015)

The role of Tribbles 1 and Tribbles 3 in cartilage turnover
by: Butcher, Andrew James
Published: (2014)

Models of cartilage vascularisation : the vasculature and its effects on developing and osteoarthritic cartilage
by: Fenwick, S. A.
Published: (1997)

An investigation of primary human cell sources and clinical scaffolds for articular cartilage repair
by: Kohli, Nupur
Published: (2016)

The chemistry of cartilage in bone dysplasias
by: Sewell, Adrian Clive
Published: (1976)

Cartilage tissue engineering : a multidisciplinary approach
by: Li, Siwei
Published: (2013)

Cartilage matrix breakdown in canine and equine models of osteoarthritis
by: Garvican, Elaine R.
Published: (2010)

A study of the structural macromolecules of articular cartilage in ostheoarthrosis
by: McDevitt, C. A.
Published: (1977)

Expression and function of NG2/HMPG in human cartilage
by: Midwood, Kim Suzanne
Published: (1999)

Identification of enzymes involved in degradation of type II collagen in cartilage
by: Nording, Jens A.
Published: (2002)

Targeted therapeutics for osteoarthritis : engineering an in vitro model of articular cartilage
by: Rogers, Catherine Mary
Published: (2011)

Outcome measurement in articular cartilage repair : exploring the patient perspective
by: Hambly, Karen
Published: (2011)

A study of the biochemical mechanisms involved in human osteoarthritic cartilage
by: Bayliss, M. T.
Published: (1976)

An in vitro model to study cartilage metabolism in Kashin-Beck disease
by: Hodgson, Paul David
Published: (2012)

Development of multi-dimensional fluorescene metrology and application to cartilage degradation in arthritis
by: Manning, Hugh Benjamin
Published: (2010)

Transcriptome analysis of cartilage in homoeostasis and osteoarthritis using deep sequencing technology
by: Xu, Yaobo
Published: (2016)