The role of the BARD1 BRCT domains in the DNA damage response

The DNA within a cell is damaged on a continuous basis by both endogenous and exogenous agents. One of the most dangerous types of damage a cell can incur are DNA Double stranded breaks (DSBs) as failure to repair these types of lesions can lead to mutations, cell death and cancer. In order to maint...

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Bibliographic Details
Main Author: Kaufmann, Aisling
Other Authors: Hiom, Kevin
Published: University of Dundee 2014
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.600777