Regulation of potassium channels by microRNA : targeting of Kir2.1 and down-regulation of inward rectifier potassium current by miR-212

Cardiac remodelling is associated with differential expression of microRNAs (miRNAs ) and down-regulation of inward rectifier K+ current (lKl) , of which Kir2.1 is the predominant molecular component . miR-212, miR-132 and miR-320 have been reported to be pro-hypertrophic miRNAs. Furthermore they ar...

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Bibliographic Details
Main Author: Goldini, Dana
Published: Queen's University Belfast 2013
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.601621