Development of nanoscale screening technology for the detection and quantification of aggregation in protein therapeutics

The use of proteins as therapeutics is one of the fastest growing sectors of the pharmaceutical industry, particularly monoclonal antibodies. However, a significant challenge in the development of such protein-based medicines is to counter aggregation of the proteins in solution (as these drugs are...

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Bibliographic Details
Main Author: Lone, Mudasir
Published: University of Nottingham 2013
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.602531