Computational design of peptide inhibitors for dengue virus

Fusion process is known to be the initial step of viral infection and hence targeting the entry process is a promising strategy to design antiviral therapy. The self-inhibitory peptides derived from the envelope (E) proteins function to inhibit the protein-protein interactions in the membrane fusion...

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Bibliographic Details
Main Author: Xu, Yongtao
Published: Queen's University Belfast 2013
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.603298