Modulation of the heat- and capsaicin-gated channel TRPV1 : role of NGF and PKC beta
Nerve growth factor (NGF), one of the major inflammatory mediators released following tissue injury, causes thermal hyperalgesia by sensitisation of the heat- and capsaicin-gated ion channel, TRPV1. The molecular mechanisms by which NGF causes sensitisation of TRPV1 remain controversial. In this the...
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University of Cambridge
2006
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Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.604706 |