Modulation of the heat- and capsaicin-gated channel TRPV1 : role of NGF and PKC beta

Nerve growth factor (NGF), one of the major inflammatory mediators released following tissue injury, causes thermal hyperalgesia by sensitisation of the heat- and capsaicin-gated ion channel, TRPV1. The molecular mechanisms by which NGF causes sensitisation of TRPV1 remain controversial. In this the...

Full description

Bibliographic Details
Main Author: Huang, J.
Published: University of Cambridge 2006
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.604706