The development of optogenetic tools for investigations into mammalian circadian organisation

Many biological oscillators are perpetuated by an autonomous molecular clockwork that generates rhythmic expression of clock genes. Whilst the periods of these endogenous rhythms deviate from 24h, daily cues in the natural environment synchronise all internal rhythms precisely to 24h. Molecular sign...

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Bibliographic Details
Main Author: Zhuang, Ling
Other Authors: Bishop, Paul; Lucas, Robert
Published: University of Manchester 2013
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.607377