Mechanisms of colorectal cancer pathogenesis : role of hypoxia

Colorectal cancer (CRC) is the third most common cancer worldwide Hypoxia plays a pivotal role in cancer, regulating cellular processes such as angiogenesis via the Hypoxia Inducible Factor (HIF) pathway. HIF-1α and HIF-2α, isoforms of the α-subunit, were previously thought to be functionally redund...

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Bibliographic Details
Main Author: Thairu, Ngayu Munga
Other Authors: Paleolog, Ewa ; Kiriakidis, Serafim ; Dawson, Peter
Published: Imperial College London 2013
Subjects:
610
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.616755