The role of innate immune system receptors in smoking related disease

Cigarette smoke induces inflammation, in part, by activation of Toll like receptor (TLR) 2 and TLR4. TLRs are present on most cells and recognize pathogen associated molecular patterns (PAMPs) and non-pathogenic molecules, known as danger associated molecular patterns (DAMPs). Activation of TLRs res...

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Bibliographic Details
Main Author: Parzych, Katarzyna
Other Authors: Mitchell, Jane ; Paul-Clark, Mark
Published: Imperial College London 2013
Subjects:
610
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.616758