HTLV-1 clonality in natural infection

Human T-Lymphotropic virus type 1 (HTLV-1) maintains persistent infection in the host by driving expansion of HTLV-1-infected T cells. However, the wide variation observed in clonal abundance in vivo remains unexplained. We hypothesize that the site of proviral integration in the host cell genome de...

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Bibliographic Details
Main Author: Melamed, Anat
Other Authors: Bangham, Charles
Published: Imperial College London 2013
Subjects:
610
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.616759