ORCTL3 : insights into the function and the structure of a novel anticancer gene

ORCTL3 was recently isolated as a gene with a tumour-speci c apoptosis activity. Its transfection into transformed cells elicits an apoptosis response, while normal cells remain unaffected. In this study I show that ORCTL3 is activated for apoptosis induction by individual tumourigenic mutations in...

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Bibliographic Details
Main Author: AbuAli, Ghada
Other Authors: Grimm, Stefan
Published: Imperial College London 2013
Subjects:
610
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.616838