Rapid removal of TACC3–ch-TOG–clathrin from kinetochore fibres during mitosis

The mitotic spindle is required to accurately separate the two duplicated copies of the genome between the two daughter cells. Errors that occur during this process can lead to aneuploidy, a hallmark of cancer. Some microtubules of the spindle are bundled by inter-microtubule bridges to form kinetoc...

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Bibliographic Details
Main Author: Cheeseman, Liam
Other Authors: Royle, Stephen; Prior, Ian
Published: University of Liverpool 2013
Subjects:
612
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.617404