Modelling HIF-1α dynamics within single cells and neurospheres

HIF-1 (Hypoxia Inducible Factor-1) is an oxygen-regulated transcription factor that mediates the intracellular response to hypoxia in human cells, targeting specific genes that promote cell survival by inducing processes such as angiogenesis and glycolysis. The HIF-1 signalling pathway has been of c...

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Bibliographic Details
Main Author: Leedale, Joseph
Other Authors: Bearon, Rachel; See, Violaine; Sharkey, Kieran
Published: University of Liverpool 2013
Subjects:
510
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.617431