Investigation into the Nrf2 signalling system dynamics and its crosstalk with the NF-κB signalling pathway at the single cell level
The Nrf2 system plays an important role in the regulation of the redox state of the cell. Protection from oxidative and genotoxic damage is achieved by Nrf2-mediated expression of antioxidant and phase-2 detoxification enzymes. The Nrf2 network topology possesses several feedback mechanisms that cou...
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University of Liverpool
2013
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.617449 |