Oxygen and pH-sensitivity of articular chondrocytes

Articular chondrocytes reside in a unique and challenging avascular environment in cartilage. During joint disease, O2 and pH levels are further reduced, and may be involved in chondrocyte dysfunction and cartilage matrix breakdown. How fluctuations in these environmental parameters affect factors s...

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Bibliographic Details
Main Author: Collins, John
Other Authors: Milner, Peter; Clegg, P. D.; Moots, Robert
Published: University of Liverpool 2014
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.617498