Enhancing the efficacy of TCR gene therapy
TCR gene therapy allows redirection of the antigen specificity of T cells by the introduction of novel TCR α and β chains by retroviral transduction. These TCR gene modified T cells can be adoptively transferred to target defined tumour antigens. The majority of TCR gene therapy studies has focused...
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University College London (University of London)
2014
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.617922 |