DNA aptamers that selectively label eukaryotic cells depending on the expression of the cell surface protein, P2X7

The ATP gated cation channel P2X7, is a cell surface protein whose function and activation is linked with several human diseases. The aim of this project was to raise DNA Aptamers targeting specifically the extracellular domain of the P2X7 protein with the hope to use these new ligands as a method f...

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Bibliographic Details
Main Author: Stephens, Matthew Jon Craig
Published: University of Portsmouth 2013
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.618284