Pharmacological effect of histone deacetylase inhibitors on pulmonary arterial hypertension

Pulmonary hypertension (PH) is characterized by structural remodelling of pulmonary arteries and arterioles, the result, at least in part, of excessive cell proliferation, resistance to cell death and hyperactive inflammatory reactions. Currently available treatments targeting the hyper-proliferativ...

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Bibliographic Details
Main Author: Chen, Chien-Nien
Other Authors: Zhao, Lan ; Wilkins, Martin ; Hajji, Nabil
Published: Imperial College London 2012
Subjects:
610
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.624053