Synthesis of inhibitors of histone deacetylase

It has been known for some years now that histone deacetylase (HDAC) inhibition exerts a variety of effects on cellular proliferation and apoptosis. The potential for use of inhibitors of HDAC in the field of cancer therapy has now been realised the first drug of this class recently being approved f...

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Bibliographic Details
Main Author: Dines, J.
Published: University College London (University of London) 2008
Subjects:
540
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.625176